Abstract
Morphogenesis of equine rotavirus strain BI in MA-104 cells was examined. Numerous virus particles were detected within the cisternae of endoplasmic reticulum in the cytoplasm of infected cells. Three types of virus particles were found: core particles 30-40nm in diameter, single-shelled particles 55-60nm in diameter, and double-shelled particles 70-80nm in diameter. The outer layer of the double-shelled particle was formed by budding from the membrane of endoplasmic reticulum. Besides, tubular and honeycomb-like structures were observed in the cytoplasm of the infected cells.