Effects of Dobutamine Infusion in Dorsally Recumbent Isoflurane-Anesthetized Horses

Abstract

Sequential changes in the heart rate (HR), cardiac output (GO) and arterial blood pressure (ABP) were compared in dorsally recumbent iso f lurane-anesthetized horses with and without dobutamine infusion. The mean ABP and GO in horses given dobutamine increased to 71.7 mmHg and 89.7 ml/kg/min, respectively, and were significantly higher than the values in the group not given dobutamine. And there were no signs o f arrhythmia in the dobutamine-treated group. The mean dobutamine administration rate was 0.86±0.3 jig/kg/mm. The results show that dobutamine infusion enhances cardiovascular function in dorsally recumbent horses anesthetized with iso f lurane.