Abstract
The chemiluminescent determination of Sulfamethoxazol is proposed by using the photo-degradation of the drug in a continuous-flow Multicommutation assembly. The light emission is the product of the drug oxidation with potassium permanganate in polyphosphoric acidic medium after irradiation (stopped-flow, 5 s) on the sample solution in alkaline medium. The method is completely automated with the aid of the emergent Multicommutation methodology, a continuous-flow modality. The new procedure allows the Sulfamethoxazol determination over the range 0,01 –250 mg l-1 with a dynamic linear range from 0,01 to 100 mg l-1; and it is applied to different types of samples. The maximum sample throughput was calculated from the avarage of base-peak wide; obtained result was 40 h-1.
