Clinical Background and Outcomes Including Changes Over Time of Barrett's Esophageal Adenocarcinoma Patients Treated with Endoscopic Submucosal Dissection in Kagoshima Prefecture, Japan

Abstract

The purpose of this study was to clarify the clinical characteristics and treatment outcomes of Barrett's esophageal adenocarcinoma (BEA) patients who underwent endoscopic submucosal dissection (ESD), including changes over time. To evaluate the clinical characteristics and outcomes of patients with BEA who underwent ESD at 6 institutions in Kagoshima Prefecture from September 2007 to July 2020. In addition, we divided the 12-year period from 2008 to 2019 into the first half and the second half, and added esophageal squamous cell carcinoma in which ESD was performed every 6 years, and compared the percentage of BEA to the total number of esophageal ESD. BEA was more common in elderly men with a history of smoking. ESD for BEA could be performed safely. The absolute number of BEAs increased over time. The number of esophageal cancers underwent ESD in this prefecture is increasing year by year, and includes a certain frequency of BEA.