The Journal of Japanese Gastroenterological Association
Online ISSN : 2435-8967
Print ISSN : 2433-3840
A Study of Cases Requiring Surgical Gastrectomy after ESD for Early Gastric Cancer
Kazuki NagaiNaohiro YoshidaManami UtsunomiyaAzusa KawasakiHiroyoshi NakanishiHisashi Doyama
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2025 Volume 9 Issue 1 Pages 25-34

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Abstract

Background and aim: Endoscopic submucosal dissection (ESD) is an increasingly popular treatment for early gastric cancer. Although the greatest advantage of ESD is that it does not require surgical gastrectomy, there are cases in which gastrectomy is necessary after ESD. The frequency and characteristics of such cases are unclear.

Methods: We retrospectively reviewed the medical records to investigate the frequency and characteristics of cases that required surgical gastrectomy after ESD.

Results: Of the 886 cases analyzed, gastric cancer was newly detected after ESD in 160 cases (18.1%), and 23 cases (2.6%) required gastrectomy. 5-year survival rates without gastrectomy were 95.0%. Reasons for requiring gastrectomy included missed endoscopies before and after ESD, interrupted hospital visits, and tumors in other organs.

Conclusion: It is important to continue high-quality endoscopic examination after ESD and to recognize that some cases may require surgical gastrectomy that cannot be prevented.

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© 2025 The Japanese Gastroenterological Association
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