Japanese Heart Journal
Online ISSN : 1348-673X
Print ISSN : 0021-4868
ISSN-L : 0021-4868
Case Reports
Improvement of Cardiac Function after Treatment with Octreotide followed by Trans-sphenoidal Surgery in an Acromegalic Patient who Presented with Congestive Heart Failure
Atsuhiro ShimakuraHisatsugu MiyakoshiHitoshi OhkuwaMasahiro KitabayashiToshio KomaiAzusa HisadaKoichiro AokiSatoru SakagamiKen-ichi KobayashiShigeo Takata
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2002 Volume 43 Issue 1 Pages 69-77

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Abstract
Cardiovascular disease is a major cause of mortality and morbidity in patients with acromegaly. We describe the case of a 43-year-old man with acromegaly who presented with severe congestive heart failure. Treatment with the somatostatin analog octreotide improved cardiac function with an increase in left ventricular ejection fraction (LVEF) from 11% to 27%. LVEF further increased to 43% after trans-sphenoidal surgery. Recovery was uneventful. We emphasize the need for early diagnosis and effective treatment of acromegaly to prevent cardiovascular complications. Octreotide therapy or trans-sphenoidal surgery, if possible, should be considered to control cardiac function even in acromegalic patients with severe congestive heart failure.
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© 2002 by the Japanese Heart Journal
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