2020 Volume 21 Issue 2 Pages 97-100
As previously reported, the administration of fat emulsions causes catheter-related bloodstream infections, which lead to a tendency to avoid administering fat emulsions under total parenteral nutrition control. One-hundred patients under total parenteral nutrition involving 15 patients with catheter-related blood stream infections were examined for whether the administration of fat emulsions can be a risk factor of infection or not, along with other factors.
Catheter-related bloodstream infections were more likely to be confirmed in patients who had been administered fat emulsions (group with infection：66.7%, group without infection：37.6%, p=0.036), along with significant differences in the value of serum albumin prior to starting total parenteral nutrition (group with infection：central value 1.9 mg/dl, group without infection：central value 2.5 mg/dl, p=0.001) and the presence of diabetes (group with infection：53.3%, group without infection：23.5%, p=0.018). On the other hand, there were no significant differences in terms of the placing position of the catheter, number of lumens, and duration of the catheter placement.
These results suggested that catheter infections increased not only with administering fat emulsions but also with hypoalbuminemia and diabetes. The nutritional management in the previous stage is required for preventing catheter-related blood stream infections.
