Abstract
In 2006, the Oita Oka Hospital decided to abolish the intracutaneous reaction test of antibiotics as a new safety policy.
After the intracutaneous reaction test's abolition allergy symptoms associated with an intravenous injection of antibiotics were found in 20 (1.22%) of 1640 cases. In one case (0.06%), which was administrated with vancomycin, an anaphylactic shock was diagnosed. In 10 cases glicopeptide antibiotics were given. The risk of anaphylaxis related to intravenous injection of antibiotics which don't require an intracutaneous reaction test, should be recognized. Appropriate intracutaneous reaction tests based on given guidelines should be carried out on patients, who need the test, while it is important to precautionary prepare a treatment for anaphylaxis and continue the patient's observation during the administration of antibiotics.
