Application of the active ingredients extracted from Hericium Erinaceus to mental health

Abstract

Hericium erinaceum (H. erinaceum) has long been used for culinary as well as for medicinal purposes. Recently, it has been reported that H. erinaceum exerts important bioactivities, including the induction of neuronal growth factor (NGF) synthesis, the inhibition of beta-amyloid peptide cytotoxicity, and protection against neuronal cell death caused by endoplasmic reticulum stress. It has also been reported that the intake of Amyloban®3399, which contains a standardized extract of H. erinaceum improves negative moods, such as irritability and anxiety, and raises incentives associated with improved concentration and motivation. The effects of the extracted from H. Erinaceus “Hericenones” and “Amiroban” are reviewed, and effect of H. erinaceum and Amyloban®3399 on mental health, including recent finding by the authors, are discussed.