Changes of Sympathetic Activity in Patient with Chronic Atrial Fibrillation and Severe Congestive Heart Failure Treated with Biventricular Pacing

Kohei Matsushita; Toshiyuki Ishikawa; Shinichi Sumita; Tsukasa Kobayashi; Hideyuki Ogawa; Noriko Inoue; Katsumi Matsumoto; Minoru Taima; Ichirou Nakazawa; Teruyasu Sugano; Tomoaki Ishigami; Kazuaki Uchino; Kazuo Kimura; Satoshi Umemura

doi:10.4020/jhrs.22.48

Case Reports

Changes of Sympathetic Activity in Patient with Chronic Atrial Fibrillation and Severe Congestive Heart Failure Treated with Biventricular Pacing

Kohei Matsushita, Toshiyuki Ishikawa, Shinichi Sumita, Tsukasa Kobayashi, Hideyuki Ogawa, Noriko Inoue, Katsumi Matsumoto, Minoru Taima, Ichirou Nakazawa, Teruyasu Sugano, Tomoaki Ishigami, Kazuaki Uchino, Kazuo Kimura, Satoshi Umemura

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Keywords: Cardiac resynchronization therapy, Pacemaker, Autonomic nervous system, Hypertrophic cardiomyopathy

JOURNAL FREE ACCESS

2006 Volume 22 Issue 1 Pages 48-51

DOI https://doi.org/10.4020/jhrs.22.48

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Abstract

The patient was a 64-year-old man with chronic atrial fibrillation with bradycardia. Left ventricular ejection fraction was 34%. He was treated with biventricular pacing. Heart failure improved from NYHA class III to II. Sympathetic nerve activity (SNA) was recorded during 6 minutes of biventricular (BV), right ventricular apical (RVA) and left ventricular (LV) pacing. SNA was significantly lower during biventricular pacing (49.5±4.0/min) compared with RVA (58.8±6.9/min, p=0.016) and LV (63.3±4.3/min, p=0.002) pacing. BV pacing improves hemodynamics and decreases SNA compared with RVA or LV pacing.

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