Alcohol-induced Ventricular Fibrillation in Brugada Syndrome

Takekuni Hayashi; Haruo Mitani; Kosaku Goto; Rieko Ishimura; Susumu Tao; Sachiko Ito; Jun Masuda; Hajime Fujimoto; Yo Fujimoto; Sugao Ishiwata; Tetsu Yamaguchi; Minoru Ohno

doi:10.4020/jhrs.25.32

Case Reports

Alcohol-induced Ventricular Fibrillation in Brugada Syndrome

Takekuni Hayashi ^†, Haruo Mitani ^†, Kosaku Goto ^†, Rieko Ishimura ^†, Susumu Tao ^†, Sachiko Ito ^†, Jun Masuda ^†, Hajime Fujimoto ^†, Yo Fujimoto ^†, Sugao Ishiwata ^†, Tetsu Yamaguchi ^†, Minoru Ohno ^†

Author information

Takekuni Hayashi ^†
Department of Cardiology, Saitama Medical Center Jichi Medical University
Haruo Mitani ^†
Department of Cardiology, Toranomon Hospital
Kosaku Goto ^†
Department of Cardiology, Toranomon Hospital
Rieko Ishimura ^†
Department of Cardiology, Toranomon Hospital
Susumu Tao ^†
Department of Cardiology, Toranomon Hospital
Sachiko Ito ^†
Department of Cardiology, Toranomon Hospital
Jun Masuda ^†
Department of Cardiology, Toranomon Hospital
Hajime Fujimoto ^†
Department of Cardiology, Toranomon Hospital
Yo Fujimoto ^†
Department of Cardiology, Toranomon Hospital
Sugao Ishiwata ^†
Department of Cardiology, Toranomon Hospital
Tetsu Yamaguchi ^†
Department of Cardiology, Toranomon Hospital
Minoru Ohno ^†
Department of Cardiology, Toranomon Hospital
Author contributions

†These authors contributed equally: Takekuni Hayashi, Haruo Mitani, Kosaku Goto, Rieko Ishimura, Susumu Tao, Sachiko Ito, Jun Masuda, Hajime Fujimoto, Yo Fujimoto, Sugao Ishiwata, Tetsu Yamaguchi, Minoru Ohno

Keywords: Alcohol, Ventricular Fibrillation, Sodium channel blocker, Diagnostic criteria

JOURNAL FREE ACCESS

2009 Volume 25 Issue 1 Pages 32-35

DOI https://doi.org/10.4020/jhrs.25.32

Details

Abstract

A 37-year-old man lost consciousness suddenly due to ventricular fibrillation (VF). After cardioversion, twelve-lead ECG showed a pattern characteristic of type 1 Brugada. An implantable cardioverter defibrillator (ICD) was implanted for Brugada syndrome. In the following three years, VF occurred eight times after consumption of alcohol. Association between the Brugada syndrome and alcohol consumption has rarely been reported. Recently, it was reported that alcohol has inhibitory effect on single cardiac sodium channel gating and it may be that alcohol acted as a sodium channel blocker in this patient. Here we report a case of alcohol-induced VF in Brugada syndrome.

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