Abstract
Metals are thought to be independent of regenerative medicine, while biodegradable polymers, biopolymers, calcium phosphate ceramics, and their composites are conventionally used as scaffold materials. However, importance of durability and strength of regenerative organs is increasing because size and morphology of target organs increase. Metals are effective materials for scaffolds for tissue engineering. Surface modification of metals is essential technique for the utilization to tissue engineering because metal surface must be controlled for adhere of cells and adsorption of biomolecules. Also, flexibility of metals is necessary.