通年性アレルギー性鼻炎に対するモメタゾン点鼻薬単独投与の効果 - 第 2 世代抗ヒスタミン薬投与で効果が不十分な症例での切り替え試験 -

松原 篤; 西澤 尚徳; 新川 秀一; 本田 耕平; 石川 和夫; 佐藤 宏昭; 太田 伸男; 鈴木 祐輔; 青柳 優; 大島 猛史; 中谷 和宏; 小林 俊光; 小川 洋; 三浦 智広; 大森 孝一

doi:10.11334/jibi.58.89

Original Article

The effects of mometasone furoate nasal spray on perennial allergic rhinitis

Atsushi MATSUBARA, Hisanori NISHIZAWA, Hideichi SHINKAWA, Kohei HONDA, Kazuo ISHIKAWA, Hiroaki SATO, Nobuo OHTA, Yusuke SUZUKI, Masaru AOYAGI, Takeshi OSHIMA, Kazuhiro NAKAYA, Toshimitsu KOBAYASHI, Hiroshi OGAWA, Tomohiro MIURA, Kouichi OMORI

Author information

Atsushi MATSUBARA
Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine
Hisanori NISHIZAWA
Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine
Hideichi SHINKAWA
Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine
Kohei HONDA
Department of Otorhinolaryngology-Head and Neck Surgery, Akita University Graduate School of Medicine
Kazuo ISHIKAWA
Department of Otorhinolaryngology-Head and Neck Surgery, Akita University Graduate School of Medicine
Hiroaki SATO
Department of Otorhinolaryngology, Iwate Medical University School of Medicine
Nobuo OHTA
Department of Otorhinolaryngology, Head and Neck Surgery, Yamagata University Faculty of Medicine
Yusuke SUZUKI
Department of Otorhinolaryngology, Head and Neck Surgery, Yamagata University Faculty of Medicine
Masaru AOYAGI
Department of Otorhinolaryngology, Head and Neck Surgery, Yamagata University Faculty of Medicine
Takeshi OSHIMA
Department of Otorhinolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine
Kazuhiro NAKAYA
Department of Otorhinolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine
Toshimitsu KOBAYASHI
Department of Otorhinolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine
Hiroshi OGAWA
Department of Otolaryngology, Fukushima Medical University
Tomohiro MIURA
Department of Otorhinolaryngology, Ohara General Hospital
Kouichi OMORI
Department of Otolaryngology, Fukushima Medical University

Keywords: JRQLQ

JOURNAL FREE ACCESS

2012 Volume 58 Issue 2 Pages 89-95

DOI https://doi.org/10.11334/jibi.58.89

Details

Abstract

We investigated the effects of monotherapy with mometasone furoate nasal spray (MFNS) in patients with perennial allergic rhinitis whose symptoms were not adequately improved by the treatment with antihistamines. After two or four weeks of administration of MFNS, the nasal symptoms (nasal discharge, sneezing, nasal discharge, and nasal stuffiness) significantly improved, The Japanese Allergic Rhinitis Standard Questionnaire (JRQLQ) showed that the patients' general state and 7 of 17 categories significantly improved. Moreover, a patient questionnaire regarding the usability of MFNS resulted in a good evaluation. These results suggested that MFNS might be useful for the improvement of nasal symptoms and QOL in patients with perennial allergic rhinitis whose symptoms are not adequately improved by treatment with antihistamines.

Corresponding author

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