Abstract
Amyloidosis is a clinical disorder caused by the extracellular deposition of particulate proteins, called amyloid, in systemic tissues. The deposition of amyloid proteins in a localized organ is known as localized amyloidosis. Amyloidosis is a rare disease, especially cases originating in the larynx. Therefore, the guidelines for amyloidosis have not yet been established. This report presents the case of a patient with localized amyloidosis of the larynx. A 75-year-old female underwent surgery for laryngeal amyloidosis at another institute. She developed recurrent hoarseness five months after the first operation and a right supraglottic mass was revealed by endoscopic examination. She was diagnosed to have immunoglobulin light chain (AL) amyloidosis of the larynx following a histopathological examination. She underwent laryngeal microsurgery using microdebrider® curettage. Microdebrider curettage allows the removal of amyloidosis safely and precisely. This case suggests two important points; 1) amyloid deposits should be excised as much as possible. Remnant amyloidosis may grow over a comparatively short period. 2) Microdebrider curettage may be beneficial for removal of amyloidosis, while preserving the original laryngeal structure.
