Abstract
The ototoxicity and bacteriostatic activity of three different solutions, Burow's solution, Povidone-Iodine (ISODINE) solution and electrolyzed strong solution (ESAS), were studied in guinea pigs. Ototoxicity was evaluated using the eighth nerve compound action potential (CAP) measured using round window electrodes. The bacteriostatic activity was evaluated by measuring the diameter of the bacteriostatic ring of an agar plate containing MRSA. Bacteriostatic activity was noted in both Burow's solution and 1/5-strength Povidone-Iodine (ISODINE) solution. Full-strength Povidone-Iodine solution showed no ototoxic effects, unlike Burow's solution. ESAS exhibited no bacteriostatic activity or ototoxic effects.
