Abstract
We herein report three cases of nasal type natural killer T-cell (NK/T-cell) lymphoma. The patients visited our hospital with complaints of nasal symptoms. All three cases complained of nasal obstruction and two complained of epistaxis. The local findings showed that a mass occupied the nasal cavity of two cases and granulation was present in one case. We performed a biopsy for all three cases, and two cases were diagnosed with NK/T-cell lymphoma based on the first biopsy, while one case was diagnosed with NK/T-cell lymphoma based on the results of a second biopsy. Two of the three cases were treated with chemoradiotherapy at our hospital. The tumor responded well to radiation therapy followed by three courses of DeVIC (dexamethasone, VP16, ifosfamide and carboplatin) combination chemotherapy. After receivingthis therapy, the patients have remained free of any symptoms or recurrence. Concurrent chemoradiotherapy using the DeVIC regimen may therefore be effective for the treatment of NK/T-cell lymphoma. When natural killer T-cell (NK/T-cell) lymphoma invades surrounding tissues, it is often associated with a poor prognosis. Therefore, an early diagnosis and early treatment are important for this disease.
