Abstract
Dexamethasone cipecilate is a corticosteroid nasal spray whose local durability has recently been improved by the introduction of a liposoluble functional group to its chemical structure. There are two devices for inhalation：a capsule loading device (Twin-lizer) and a multiple inhaler. In this study, we compared the handling and tolerability of these two nasal spray devices in patients with allergic rhinitis. The characteristics of device handling and preferences were assessed according to a questionnaire, with the responses recorded on a five-point ordinal scale. Consequently, the device handling results showed that the multiple inhaler was rated more favorably than the Jetlizer inhaler in terms of the ease of correct inhaler use, and 63.1% of the patients reported that they would be happy to receive the multiple inhaler. In addition, the multiple inhaler was preferred by 85.7% of physicians with respect to the instructions for application. Therefore, the administration of dexamethasone cipecilate with a multiple inhaler may be superior in terms of patient compliance with instructions.
