Abstract
Recently, refractory acute rhinosinusitis caused by drug-resistant Streptcoccus pneumoniae (DRSP) and ampicillin (ABPC)-resistant Haemophilus influenzae has been reported. Drug-resistant bacterial transmission through infants attending nursery school is considered to be a probable cause of such infection. I investigated the relationship between living with infants attending a day nursery and the frequency of detecting drug-resistant bacteria, and also evaluated the drug sensitivity of the detected bacteria in adult patients with acute rhinosinusitis. The subjects consisted of 670 adult patients who presented to my clinic with acute rhinosinusitis between July 2010 and June 2013. DRSP and ABPC-resistant H. influenzae was detected at a significantly higher frequency in the patients living with infants who attend nursery schools than in those not living with such infants. The identified bacteria tended to have poor drug sensitivity. To treat acute rhinosinusitis in adult patients with infants who attend nursery schools, antibacterial drugs should be carefully selected while considering the possibility of potential drug resistance and the severity of infection should also be evaluated.
