Abstract
My own tinnitus cerebri, which I have experienced for 20 years, was treated with a fibrinolytic enzyme, lumbrokinase, which is extracted from a type of earthworm. The tinnitus clearly decreased over a few days, and disappeared almost completely when the dosage was increased. Thrombotic microangiopathy at the Wernicke area should be considered as a treatment for tinnitus cerebri. This anoxic condition at the tripartite synapse results in the constant overflow of glutamic acid (due to the decreased function of the astroglia), causing glutamine – glutamic – acid recycling. The neurons are then constantly excited, resulting in tinnitus without audio stimulation.