A case of IgG4-related periarteritis of the left temporal arteries

Abstract

Immunoglobulin G4 (IgG4) -related disease was first proposed in relation to autoimmune pancreatitis in 2001, and is characterized by an elevated serum concentration of IgG4 and tissue infiltration by IgG4-positive plasma cells. We herein report a case of IgG4-related periarteritis of the left temporal arteries. A 60-year-old patient visited our hospital complaining of a tumorous lesion in his left temporal region. The local findings showed the formation of tumor in the left temporal region ; the tumor was detected by enhanced computed tomography (CT). We resected the tumor under general anesthesia. An immunohistochemical examination revealed numerous IgG4-positive plasma cells around the temporal arteries. The serum concentrations of IgG4 at 20 days after surgery was 105 mg/dℓ ; this decreased to 92.8mg/dℓ at 60 days after surgery. There were no complications and the post-operative result was acceptable.