2019 Volume 65 Issue 2 Pages 54-60
We experienced two cases of subacute to chronic invasive paranasal fungal infection with Aspergillus that occurred in patients who were elderly but who had no underlying disease that would otherwise impair their immune function and were difficult to diagnose and treat. Invasive fungal rhinosinusitis is fatal and has a poor prognosis if it progresses from the paranasal sinuses to the orbit, cavernous sinus, and cranium. However, the disease was brought under control by curetting the lesion as much as possible and administering antifungal drugs thereafter. The number of elderly people is expected to continue to increase in Japan, along with cases of invasive paranasal fungal disease that follow a chronic course. As chronic invasive fungal rhinosinusitis is an inflammatory disease of the paranasal sinuses, it is essential to accurately carry out its diagnosis and treatment.
