Two cases of rhinocerebral mucormycosis

Abstract

Rhinocerebral mucormycosis is a rare disease that rapidly spreads to the brain or orbit, and which is a potentially life-threatening condition. We present our clinical experience with 2 cases. Case 1 : A 73-year-old male who received dialysis due to diabetes, presenting with hematuria, was admitted to our hospital for emphysema cystitis. During the administration of antibiotics, he became unconscious and developed rhinocerebral mucormycosis with cerebral infarction. He was treated with an antifungal drug but died of aspiration pneumonia. Case 2 : A 56-year-old female was admitted to our hospital for acute myeloid leukemia. She developed eyelid swelling during chemotherapy. Antibiotics and antifungal drugs were administrated, but she became blind and developed rhinocerebral mucormycosis. She was treated with an antifungal drug and surgery but died of acute myeloid leukemia.