Clinical course of 10 cases of otitis media with ANCA-associated vasculitis

Abstract

From 2014 to 2021, we examined the clinical features of 10 cases diagnosed with otitis media with ANCA-associated vasculitis (OMAAV) at our hospital. The first visit dates were 2014, 2015, and 2017 (1 case each), 2019 and 2020 (3 cases each), and 2021 (1 case). The period from the first visit to the start of treatment ranged from seven days to five months, and treatment was able to be started within 26 days from the first in all but 1 case (first visit in 2014). According to the Ministry of Health, Labor, and Welfare standards, ANCA-associated vasculitis was diagnosed in four cases with definitive granulomatosis with polyangiitis (GPA) and six with suspected GPA. Hypertrophic pachymeningitis was observed in one case. Facial nerve palsy was observed in two cases, ultimately improving in both cases. All patients remained alive during the observation period. The diagnostic criteria proposed in 2015 enabled the early diagnosis of OMAAV and facilitated early treatment in collaboration with collagen physicians.