A case of systemic amyloidosis with a laryngeal mass

Abstract

We herein report a case of systemic amyloidosis with a sporadic mass lesion in the larynx. An 85-year-old man complained of dysphagia and discomfort in the larynx. He was hospitalized for an examination, and computed tomography revealed a laryngeal mass. He was transferred to our hospital, but we found only a lesion in the epiglottis. We biopsied the lesion under general anesthesia, and the pathological diagnosis was amyloidosis. Increases in plasma cell counts and abnormalities among the surface antigens of plasma cells were observed in the bone marrow, indicating systemic amyloidosis. Given these findings, he was diagnosed with systemic amyloidosis derived from plasma cell disease. Amyloid neuropathy or amyloid myopathy may cause dysphagia. Dental equipment and rehabilitation improved his swallowing function, and he regained his ability to eat.