2024 Volume 70 Issue 2 Pages 78-83
The nasal and paranasal sinus regions contain a wide variety of tissues, including the skin, mucous membranes, and cartilage, which are the primary sites of origin for a wide variety of benign and malignant tumors. In many cases, blood sampling, immunohistochemistry, and a chromosomal analysis are insufficient for their diagnosis. In the present case, multiple biopsies were performed for a patient with nasopharyngeal swelling, and HE staining, immunostaining, flow cytometry, and chromosome analysis were conducted. However, a definitive diagnosis could not be established. Genetic testing was performed, and a diagnosis of peripheral T-cell lymphoma of unspecified type was made. If malignant lymphoma is suspected, genetic testing for TCR monoclonality may be useful in differentiating it from other diseases.
