Abstract
Seventy-five ears of sensory-neural deafness such as acoustic trauma, Streptomycin poisoning, presbycusis, cochlear vascular disorder and non-classified deafness were treated with α-tocopherol acetate, 150-450 mg per day by oral administration for several weeks.
Recently, many biochemical actions of vitamin E were found in addition to antisteril action. The antioxydatic, vasodilative and hemodynamic actions seems to be available for pathologic conditions of the inner ear.
Results were determined to be effective when the gain in post-treatment was greater than 10 db in two of three methods of which computations were as follows; average of 125, 500, 1000, 2000, 40000 and 8000 cps, average of speech range cycles (500, 1000 and 2000 cps) and average of 250, 1000 and 4000 cps.
The efficacy ratio for hearing loss was 17% (13 ears in 75). Thinnitus in 19 ears out of 54 ears were disappeared or improved (35%). Vertigo in 4 cases, headache in 4 cases and several neurotic complains were also improved.
High ratio of efficacy was obtained in non-classified deafness, Streptomycin poisoning and acoustic trauma.
