Abstract
Department of Otolaryngology, Yamaguchi University School of Medicine, Ube, Yamaguchi-ken, Japan Allergic rhinitis is among the atopic allergic diseases. Sera from patients with atopic disease possess reaginic antibodies that are positive Prausnitz-Kustner reaction substances. Recently, a new immunoglobulin class-IgE-was discovered, in which the reaginic antibodies are present in high concentration. The chemical structure and biologic properties of this new immunoglobulin is described, and further investigative efforts for IgE was proposed to clarify the defence mechanism of IgE.
