Abstract
It was 27 years ago that the first case of streptomycin deafness had been reported by Hinshow and Feldman in Mayo Clinic. During this period, the streptomycin deafness has been reformed again and again, and we, clinical otologists, in studying the problems on the disease, have been puzzled many time. Very recently, however, as the results of the excellent number of the observations on the streptomycin deafness, it becomes possible to prevent the occurence of severe hearing loss due to this drug. In this paper, otologists' hostility to the disease was historically reviewed and our pains and gains were briefly discussed.