Measurement of Potassium Ion Concentration in the Inner Ear Fluid with Liquid Ion-Exchanger Microelectrode

Abstract

Ion specific liquid ion-exchanger microelectrode has been successfully applied to the inner ear fluids. With this electrode, continuous and reliable measurement of the potassium ion concentration became possible.
Pathogenesis of the inner ear deafness such as Meniere's disease are thought due largely to imbalance of potassium and sodium ions in the inner ear fluids. This technique provides a useful tool for the better understanding of the inner ear pathology. Technical aspects of making electrodes and detailed technical advice in applying to the living animal have been presented.