jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Effect of Radiation Therapy on Difficult Curable Ulceration of the Pharynx
Koichi SHIBATAIkuichiro HIROTOTadashi NAKASHIMAAkira YASUKOCHI
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1975 Volume 21 Issue 4 Pages 640-646

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Abstract
Six cases with highly resistant ulceration of the pharynx of unknown etiology were treated by irradiation. All of them had been already ineffectivelly treated with various kinds of therapeutic agents such as steroid hormone, anti-histamines, vitamines, antibiotics, anti-plasmines etc.
Eighty rads or 100 rads of irradiation were given once a week. Total amount was 1000 rads. Irradiation was remarkably effective on the pharyngeal ulcer in all cases ; however, two of them died of malignant lymphoma of the nose and of severe hepatitis a few months later. In another case the ulceration recurred at the same portion two months later, and re-irradiation of tumor dosis of 60Co showed good result.
In view of the effective dosis of irradiation, the etiology of these ulcerations may be classified to the collagen disease such as autoimmune disease and the malignant lymphoma.
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