Abstract
Primary squamous cell carcinoma of the thyroid gland is rare and high malignant neoplasma. During past six years, we treated 87 cases of thyroid carcinoma in our clinic, among them a case, 43-years-old female, of primary squamous cell carcinoma was reported herewith.
She had been aware of the left thyroid tumor since nine years with silent symptome. Recently, this left thyroid tumor began to grow in size aggressively with dyspnea and hoarseness in a few days. Histological examination revealed follicular adenocarcinoma showing anaplastic medullary growth in the primarily extripated struma and poorly differentiated squamous cell carcinoma in the local recurrent mass. Metaplasia from follicular adenocarcinoma to squamous cell carcinoma was supposed as the pathogenesis of this case. Radiation therapy and chemotherapy of 5Fu and BLM were not effective.
