jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Immunoserological Study with the OEP-HA Reaction (Passive Hemagglutination) on the Pseudomonal Otitis Media
Norimasa MIYAKOGAWA
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1981 Volume 27 Issue 1Supplement1 Pages 189-194

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Abstract
Pseudomonas infection has been increasing in number these days and pseudomonal otitis media have been found in the otolaryngological practice. Pseudomonal infections are caused by bacterial substitution phenomena, burns, tissue transplantations, major surgeries, endoscopic procedures, intensive radiation therapies and steroid therapy. We have great number of problems to treat this infection.
The author applied hemagglutination (OEP-HA reaction) to 33 patients of pseudomonal chronic otitis media and obtained the results on specific antibody to this bacillus. OEP (=Original Endotoxic Protein) is protective antigen located in cell wall of pseudomonas aeruginosa and is found in the group specific in its protective antigenicity. Antibody titer in normal human sera is under 1: 80. The specific antibody titer in 65 strains (33 patients) was ranged from under 1: 40 to over 1: 2560. The rate of 17 positive strains (over 1: 160) was 26.2 %. The antibody titer of most control strains was within normal limit.
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