Abstract
A vocal cord polyp (1 mm in diameter) was obtained from a 56 years old man who died of cardiovascular disease. The specimen was extracted at the time of autopsy 3 hours after death and prepared for examination.
Routine histopathological study revealed the hyaline deposition and submucosal hemorrhage. When consecutive sections were studied, it became evident that the basal layer of the stratified epithelium was broken and connective tissues appeared intradermally. Immunoenzymatic and immunofluorecent examination revealed the presence of IgA, IgG and other immunoglobulins in the polyp.
Fluolescence for fibrin corresponded the distribution of hyaline deposition. Fluorescence for IgA and IgG was also found throughout the submucosal stroma beneath the stratified epithelium. Immunological survey of the vocal cord polyp is now underway
