1982 Volume 28 Issue 5Supplement3 Pages 1010-1017
A chronic relapsing form of allergic encephalomyelitis and neuritis which was characterized in man was induced experimentaly by single sensitization of immature and adult Hartley guinea pigs. Among them, a few animals showed a severe hearing loss. Histological studies of their cochlea showed a severe loss of ganglion cells and hair cells. The organ of Corti was atrophied but Stria vascularis had no changes. There was granular precipitate in Scala media and Scala tympani. Thus there may be possibilities that the chronic encephalomyelitis could affect the inner ear as the results of our experimentes. The sensorineural hearing loss with unknown etiology may be considered to some immunologic diseases.
