Serological Studies of Herpes Simplex Virus on Patients with Sudden Deafness.

Abstract

In 221 patients with sudden deafness, who came to our hospital within 2 weeks after the onset, herpes simplex virus (HSV) complement fixation (CF) test was performed. Forty six percent of these cases showed positive CF antibody and it was statistically significant against normal control data.
The paired serum tests were performed in 98 cases. Significant changes of CF antibody titers were found in 10 cases (10.2%) of these 98 cases.
In these particular cases, HSV was suspected as one of the causative factors of sudden deafness.
Clinically, no apparent differences were observed between sudden deafness caused by HSV and that by other causes.