Abstract
Thirty one white guinea pigs were exposed to sound(white noise, 100dB. SPL. or 4kHz. pure tone 115dB. SPL., 2 hours)and infrasound vibration(Frequency 10Hz., amplitude 5mm., 4 or 6 hours), independently or simultaneously to study the influence of infrasound vibration upon the cochlea. After the exposure, amplitude and latency time of the AP of the electrocochleogram was studied by inserting a needle electrode into the cochlea under intraperitonel anesthesia. The electrocochleogram was obtained by averaging response to 256 clicks at a rate of 8 per second. The results showed that the amplitude of the AP significantly decreased when guinea pigs were exposed to both 4kHz. pure tone and infrasound vibration(P≤0.05). The latency time of the AP was slightly prolonged when they were exposed to the sound and infrasound vibration simultaneously. These results imply that the exposure to sound and infrasound vibration have an effect upon the physiological function of the cochlea of the guinea pig.
