Abstract
The clinical effects of Merislon (Betahistine dimethyl sulfonate) were studied on 23 patients with vertigo, principally Meniere's disease. Merislon was effective in about 90% of 23 cases. As to subjective symptoms, the frequency and intensity of vertigo were prominently improved, but no improvements of tinnitus and hearing impairment were observed. As for objective findings, curative effects on disappearance of abnormal nystagmus such as spontaneous nystagmus and improvement of the stepping test were observed. No obvious side effects were seen, even in the long term administration cases. Thus Merislon seemed to be effective for treatment of vertigo. principally peripheral vertigo.
