Abstract
Primary and metastatic adenocarcinoma and adenoid cystic carcinoma in the head and neck regions were treated by CAP therapy, a multiple combination chemotherapy consisting of cyclophosphamide (C), THP or adriamycin (A), and cisplatinum (P). This therapy was given once to 10 patients with primary adnocarcinoma, 5 with adenoid cystic carcinoma, and 2 with metastatic adenocarcinoma from the stomach. Following results were obtained: Complete response was detected in 6 patients and partial response was detected in 3 patients of adenocarcinoma. Efficacy rate was 75%. No response was observed in patients of adenoid cystic carcinoma. The average efficacy rate for the entire series was 53% (9/17), and the duration of efficacy ranged from 28 to 278 days (mean, 96.5 days).
