Study on distant metastases of cancer of the larynx and hypopharynx

Abstract

Distant metastases were detected in 20 cases (5.6%) of 358 patients with laryngeal cancer and 16 cases (19.0%) of 84 patients with hypopharyngeal cancer treated from July, 1978 to December, 1983 in the Center for Adult Diseases, Osaka. The most common sites of distant metastases were the lung, the bone and the liver in the order of frequencies, in both malignancies. The development of distant metastases is higher in patients with T3-T4, and N positive supraglottis or transglottis, T2 anterior commissure type glottis, and piriformis sinus cancer.