Therapeutic effects of Dilazep on patients with vertigo

Abstract

One hundred and two patients at several institutions with peripheral and central vertigo or dizziness were orally administered Dilazep hydrochloride to analyze its clinical efficacy. The evaluation by the attending otolaryngologists show improvement rates as high as 85.3% against subjective symptoms of vertigo or dizziness, 70.0% on objective findings, and 82.7% in total. Scoring assessment also showed high rates of improvement with 89.2% for subjective symptoms, 81.3% for objective findings, and 89.2% in total. The rate of improvement was higher in patients with peripheral vertigo and dizziness than in patients with central vertigo and dizziness. It was similarly higher for subjective symptoms than for objective symptoms. It was also observed that the rate of improvement becomes higher in proportion to the duration of the administration. Safety analysis showed side effects in four of the 106 cases (3.8%), the side effects were temporary and none were serious.