Abstract
Sudden deafness was treated with low molecular weight dextran (LMD) and prostaglandin E1 (PGE1) for a comparative study with the steroid therapy. As a result, the complete recovery and remarkable improvement of hearing was noted in 68.1 percent in the LMD and PGE1 group against 49.6 percent in the steroid therapy group. In patients who received these treatment more than seven days after the onset, the incidence of the complete recovery and remarkable improvement of hearing was significantly higher in the LMD and PGE1 group than in the steroid group. A significance was recognized between the LMD and PEG1 group and steroid group in cases of severe hearing loss with the hearing level at the first visit being 61 to 90 dB. The results above suggest that a combinational use of LMD and PGE1 may be useful.
