Abstract
A case of laryngeal spindle cell carcinoma is reported. The patient was 54-year-old female who presented with symptoms of hoarseness and dyspnea. The histogenesis of the spindle cells was evaluated by HE, immunohistochemical staining and an electron microscopic analysis. The immunohistochemical findings revealed that the spindle cells had a positive cytokeratin and vimentin immunoreactivity. In addition, an electron microscopic study revealed that such epithelial ultrastrucctures as the desmosomes and tonofilament were found in the spindle cells.