jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Is pranlukast effective for nasal symptoms due to AIA with nasal polyps?
Satoshi OGINOMorihiro IRIFUNEHiroe Goro
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1997 Volume 43 Issue 6 Pages 813-817

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Abstract
We examined the effectiveness of pranlukast for nasal symptoms in 7 cases of aspirin-induced asthma (AIA) with nasal polyps. 450mg (4 capsules) of pranlukast was administered for 4 weeks. At the end of the study, we assessed the efficacy according to changes in the nasal symptom scores. One patient showed a moderate improvement, and another showed a slight improvement, however, the other 5 patients showed no change. In addition, one case complained of mouth dryness as a side effect. Based on the above findings, pranlukast is thus considered to be very effictive for the treatment of nasal symptoms due to AIA, especially when also associated with nasal polyps.
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