Abstract
In 38 patients who demonstrated tinnitus with hyperlipidemia the relationship between the change in the serum lipoprotein value and a reduction of tinnitus was evaluated. In 25 of the 38 patents (65.8%) a reduction of tinnitus was recognized. Regarding the total cholesterol and phospholipid levels, no remarkable relationship was seen between the change in the serum level and the degree of tinnitus after the administration of hyperlipidemic agents. On the other hand, the amount of both triglyceride and non-estelized fatty acid decreased remarkably in the effective group which showed a decrease in tinnitus intensity. In 14 of 17 patients, the serum value of triglyceride decreased from an abnormally high level to normal levels. Of all the patients who showed an abnormally high serum level of triglyceride, 17 patients later showed a normal serum level after the administration of anti-hyperlipidemic drug. In addition, 14 of them (82.4%) also showed an effective reduction of tinnitus. Based on these findings, the administration of anti-hyperlipidemic drug is thus suggested to be useful in treating patients suffering from tinnitus with hyperlipidemia, especially patients with hypertriglycemia.