Abstract
The result of radiation therapy on 64 patients with T1, T2N0 glottic carcinoma treated from 1985 to 1995 were reviewed. In these patients, 39 and 25 were classified as T1 and T2, respectively. The total exposure radiation dosage due to bilateral irradiation ranged from 60Gy to 76Gy. After radiation therapy, local recurrence was recognized in 14 cases (22%) overall, including 6 T1 cases (15%) and 8 (32%) T2 cases. Regarding the second treatment in the cases with local recurrence, a total laryngectomy and a laser cordectomy were performed in 12 and 2 cases, respectively. Larynx preservation was achieved in 87, 72% and 82% of the T1, T2 and overall cases, respectively. The ultimate control rate of disease, including a salvage operation, was 97% and the 5 year survival rate was 95%. For the preservation of voice function accompanied by a good prognosis, a partial ressection of the larynx could be applied in some cases with local recurrence after radiation therapy.
