Abstract
Voice disorders have been regarded as one of the major symptoms of GERD. We made a clinical study of voice disorders in 135 cases who diagnosed as GERD based on pharyngolaryngeal and esophageal findings. Out of the 135 cases, 45 cases complained of voice problems on a questionnaire survey before PPI treatment. Perceptual evaluaion using GRBAS rating scale showed that 18 cases out of the 45 had some degree of hoarseness. Laryngeal examination revealed different types of organic change in 20 of the 45 cases, including granuloma in 7, corditis in 4, sulcus vocalis in 4, polypoid vocal cord in 3 and vocal cord polyp in 2. After the administration of PPI for 8 weeks, subjective voice complains improved in 19 cases(40%). On the other hand, hoarseness improved in 2 cases out of the 18 cases in perceptual evaluation after the treatment. As for laryngeal findings, corditis improved in all 4 cases and granuloma improved in 4 out of the 7. It was considered that PPI treatment was effective for voice disorders in cases in which GERD was suspected by clinical examinations.