jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Faropenemsodium(FRPM)in otorhinolaryngological infections
Junko INABAMitsuru OHASHIKeiji MATSUDAShizuo KOMUNEKouji MATSUURAKatsuhiro TOYAMAMika TAKENAKAMasayuki SADANAGAKouji TORIHARA
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2001 Volume 47 Issue 3 Pages 208-215

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Abstract
We tried to investigate the effectiveness of Faropenemsodium (FRPM) in the treatment of infections otorhinolaryngological disease. FRPM was administered to 91 patients. Clinical efficacy was 65.5% (21/32 cases) n ear diseases, 81.8% (18/22) in nasal diseases, 78.8% (26/33) in pharyngeal and laryngeal diseases, 75% (3/4) in other diseases (acute parotitis 1/1, lymphadenitis 2/3). The total clinical efficiency was 74.7% (68/91). All patients were divided into 4 groups in order to evaluate the additional effects of treatments other than FRPM as follows: 1) 55% (11/20) received FRPM alone 2) 84.1% (37/44) received FRPM and analgesics 3) 80% (8/10) received FRPM and local treatment 4) 70.6% (12/17) received FRPM as well as both analgesics and local treatment. Side effects were only observed in two cases who developed diarrhea, however, no serious side effects were seen. Bases on these findings, we consider FRPM to be a useful chemotherapeutic drug for the treatment of infections disorders in the field of otorhinolaryngology.
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