Abstract
Twenty-five patients with globus sensation due to gastroesophageal reflux disease were treated with oral administration of ransoprazole or rabeprazole. All patients underwent indirect and fiber optic laryngoscopy, upper gastrointestinal fiberscopy, and blood examination. The reflux esophagitis and hiatal hernia were observed in four and eight patients, respectively. Ten patients were treated with 30mg/day ransoprazole, and fifteen patients were treated with 20mg/day rabeprazole. The efficacy of ransoprazole and rabeprazole was 70% and 67%, respectively. Both ransoprazole and rabeprazole were effective to patients with globus sensation due to gastroesophageal reflux disease.
