Abstract
The initial effects of olopatadine hydrochloride treatment were evaluated in 17 patients with cedar pollinosis. The administration of olopatadine hydrochloride (5mg) twice daily before cedar pollen begins to disperse in earnest was found to help prevent any aggravation of the patient symptoms. Such an aggravation of the symptoms tended to be suppressed in the initial treatment group in comparison to the non-initial treatment group. This tendency was also especially strongly observed regarding the symptom medication score. There was also no incidence of any discontinuation of the drug administration due to any adverse effects. The results of our study therefore demonstrated the safety and effectiveness of this agent.