Abstract
The efficacy of combination therapy consisting of an anti-histamine and an anti-leukotriene was compared in monotherapy using each drug in patients with Japanese cedar pollinosis. Twenty-two patients were randomized into three groups, namely, those receiving olopatadine, pranlukast or a combination of the two drugs, and then they were treated for four weeks. The nasal symptoms improved in the olopatadine and combination groups. These results demonstrated that olopatadine is an effective drugs for improving nasal symptoms.
